Kidney protective and burn healing effect Plantago lanceolata aqueous extract on albino male mice

نویسندگان

چکیده

This study aimed to in vivo evaluate the effect of Plantago lanceolata aqueous extract on kidney function test ( total serum protein, urea and creatinine) anti-inflammatory through determined day require heal burn mice skin.. is a species flowering plant Plantaginaceae (plantain) family, seems be very versatile addition medicine cabinet being an antifungal, antioxidant, analgesic many other medicinal application. Two design groups used: one for protective activity. In activity eight were assessed: group I: treated with first dose (500 mg\kg) , II: second (250 mg\kg), Group III :negative control; administrated distill water, IV: CCL4, V: An interaction between CCL4 (0.02 mg\kg CCL4+ 500 dose), VI: 250 VII:: +0.02 CCL4), VIII: CCL4). While activity, three Mice without any treatment, III: silverin cream burns. The results showed that drug produced experiential decrease protein concentration (3.76±0.15 g\dL) contrast negative control (5.40±0.26 g\dL), while direction at all doses tested instigated increase (7.46±0.40, 6.43±0.41, 6.43±0.41 5.60±0.73 g\dl) (V, VI, VII VIII respectively).Creatinin also match by increasing their concentrations (0.80±0.10 mg\dL ) as compared (0.3±0.1 mg\dl) ability cause reduction dependent manner according deferent treatments (0.60±0.10, 0.62±0.15, 0.36±0.05 0.50±0.10 (group V,VI,VII respectively). declared 14 days positive controls which 28 18 days) respectively. All obtained may attributed active secondary metabolite presented like tannin, mucilage silicic acid etc.

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ژورنال

عنوان ژورنال: International Journal of Science and Research Archive

سال: 2023

ISSN: ['2582-8185']

DOI: https://doi.org/10.30574/ijsra.2023.8.1.0041